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Department of Microbiology, University of Chicago, Chicago, Ill., U.S.A.
Established (laboratory) strains and fresh isolates of herpes simplex virus from patients with skin and genital lesions were classified into four groups depending on their effects on the social interaction among infected HEP-2 cells. The groups comprised strains causing (1) rounding of cells but no adhesion or fusion, (2) loose aggregation of rounded cells, (3) tight adhesion of rounded cells, and (4) fusion of cells into polykaryocytes. Protype strains from each group were found to differ with respect to immunologic specificity, buoyant density in CsCl solutions and stability at 40°.
Received 6 September 1967;
accepted 13 November 1967.
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P. M. Beard, C. Duffy, and J. D. Baines Quantification of the DNA Cleavage and Packaging Proteins UL15 and UL28 in A and B Capsids of Herpes Simplex Virus Type 1 J. Virol., February 1, 2004; 78(3): 1367 - 1374. [Abstract] [Full Text] [PDF]
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M. Tanaka, H. Kagawa, Y. Yamanashi, T. Sata, and Y. Kawaguchi Construction of an Excisable Bacterial Artificial Chromosome Containing a Full-Length Infectious Clone of Herpes Simplex Virus Type 1: Viruses Reconstituted from the Clone Exhibit Wild-Type Properties In Vitro and In Vivo J. Virol., December 20, 2002; 77(2): 1382 - 1391. [Abstract] [Full Te |
