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J Gen Virol 66 (1985), 367-371; DOI 10.1099/0022-1317-66-2-367
© 1985 Society for General Microbiology
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The Reversion of Temperature-sensitive Mutants of Encephalomyocarditis Virus upon Serial Passage in Three Continuous Cell Lines

Roger J. Radloff

Department of Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, U.S.A.

Several temperature-sensitive mutants of encephalomyocarditis virus were serially passed numerous times in HeLa, L929 and BHK-21 cells. The reversion of most of the mutants occurred most rapidly in BHK-21 cells and least rapidly in HeLa cells.

Keywords: EMC virus, reversion, serial passage

Received 23 January 1984; accepted 16 October 1984.




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Copyright © 1985 by the Society for General Microbiology.